Clinical Audit: Magnesium Threonate & Neural Plasticity

Audit Status: 9.2/10 Precision Score | Lead Researcher: Prince Ambrose Edonojie

1. Biological Mechanism

Magnesium L-Threonate (MgT) is the only magnesium compound proven to effectively cross the blood-brain barrier. By increasing magnesium concentrations in the cerebrospinal fluid, it enhances synaptic density in the hippocampus, the brain’s primary center for learning and memory.

2. Clinical Evidence

• Synaptic Potentiation: Studies show a 15% increase in functional synapse density.
• Cognitive Age Reversal: Randomized controlled trials suggest a reversal of brain aging by up to 9 years in specific cohorts.

3. Optimization Protocol

For maximum neural uptake, distribute dosage: 667mg in the AM and 1,333mg 1-hour prior to sleep. Avoid co-ingestion with high-zinc substrates to prevent absorption competition.